David Kleinfeld, Lan Luan, Partha P.Mitra, Jacob T.Robinson, Rahul Sarpeshkar Kenneth Shepard, ChongXie, Timothy D.Harris. Can One Concurrently Record Electrical Spikes from Every Neuron in a Mammalian Brain?. Neuron, 5 September 2019, DOI: 10.1016/j.neuron.2019.08.011

Physical limits do not preclude simultaneous recordings of all spikes in neocortex
Future electrodes need nontraditional materials and fabrication procedures
Challenges for dense recording include heat dissipation from interface electronics